abstract：:Mutations in ilvO, the operator site for operon A of the ilv region of E. coli K-12, are reported to cause a cis dominant derepression of the operon A gene products and to map between ilvC and ilvA. Studies reported here demonstrate that the F25 episome which does not carry the region between ilvC and ilvA but only il...

journal_title：Genetics

authors： Cohen BM,Jones EW

更新日期：1976-06-01 00:00:00

abstract：:Recessive lethal or semilethal alleles at the T/t locus in the mouse generate new t-variants, with characteristics different from the parent allele at a rate of about 10(-3). Almost invariably the variant chromosome carries marker genes derived from the opposite parental chromosome. New t-mutations obtained in this wa...

journal_title：Genetics

authors： Bennett D,Dunn LC,Artzt K

更新日期：1976-06-01 00:00:00

abstract：:A system for genetic analysis in the cellular slime mold P. violaceum has been developed. Two growth-temperature-sensitive mutants were isolated in a haploid strain and used to select rare diploid heterozygotes arising by spontaneous fusion of the haploid cells. A recessive mutation to cycloheximide resistance in one ...

journal_title：Genetics

authors： Warren AJ,Warren WD,Cox EC

更新日期：1976-05-01 00:00:00

abstract：:Additional experiments with homologous as well as heterologous hybridization confirmed our previous finding in Sciara coprophila that XX females have nearly twice the number of ribosomal RNA cistrons as XO males. A comparison between two different X' chromosomes revealed that only the one carrying the irradiation-indu...

journal_title：Genetics

authors： Gerbi SA,Crouse HV

更新日期：1976-05-01 00:00:00

abstract：:137Cs-gamma irradiation of bacteriophage T4 induces large deletions plus a variety of types of point mutations. All mutations arise with single-hit kinetics, and all by a misrepair process. The estimated point mutation rate is 1.5 X 10(-9) per locus per rad. ...

journal_title：Genetics

authors： Conkling MA,Grunau JA,Drake JW

更新日期：1976-04-01 00:00:00

abstract：:Twelve mutations affecting nuclear migration, a major developmental phase in Schizophyllum commune, display a complex pattern of complementation and recombination. They are expressed only when a genetic factor controlling this phase of development, the B incompatibility factor, is operative. All twelve mutations are l...

journal_title：Genetics

authors： Dubovoy C

更新日期：1976-03-01 00:00:00

abstract：:A supposed sporulation-deficient mutation of Saccharomyces cerevisiae is found to affect mating in haploids and in diploids, and to be inseparable from the mating-type locus by recombination. The mutation is regarded as a defective a allele and is designated a*. This is confirmed by its dominance relations in diploids...

journal_title：Genetics

authors： Kassir Y,Simchen G

更新日期：1976-02-01 00:00:00

abstract：:The Yanomama Indians are a South American tribe distributed over an irregular area approximately 200 X 300 miles. The gene frequencies observed at 12 loci in 47 villages within this area have been analyzed for the occurrence of clines. Apparently significant clines are observed for alleles of the Rh, MNSs, Kidd, Gm, I...

journal_title：Genetics

authors： Ward RH,Neel JV

更新日期：1976-01-01 00:00:00

abstract：:We have investigated the order of the four genes cyc1, rad7, SUP4, and cdc8 which form a tightly linked cluster on the right arm of chromosome X in the yeast Saccharomyces cerevisiae. Crossing over and coconversion data from tetrad analysis established the gene order to be centromere-cyc1-rad7-SUP4. Also cdc8 appeared...

journal_title：Genetics

authors： Lawrence CW,Sherman F,Jackson M,Gilmore RA

更新日期：1975-12-01 00:00:00

abstract：:Two replications of a complete diallel cross experiment were performed among four partially inbred lines of mice. These inbred lines originated from a random-bred ICR strain and were produced by 12 generations of full sibbing (F congruent to 92%). Individual body weight was recorded for each animal at 12, 21, 42 and 5...

journal_title：Genetics

authors： Jamison MG,White JM,Vinson WE,Hinkelmann K

更新日期：1975-10-01 00:00:00

abstract：:Genetic control over chromosome stability in the interspecific hybrid embryos of Hordeum vulgare and H. bulbosum has been hypothesized to reside on specific chromosomes. In this study, crosses between the primary trisomic lines for the seven different H. vulgare chromosomes and tetraploid H. bulbosum revealed that bot...

journal_title：Genetics

authors： Ho KM,Kasha KJ

更新日期：1975-10-01 00:00:00

abstract：:A second chromosome line of Drosophila melanogaster (Symbol: T-007) has previously been shown to be responsible for the induction of male recombination. In the present investigation, the genetic elements responsible for this phenomenon have been partially identified and mapped. A major element (Symbol: Mr, for Male re...

journal_title：Genetics

authors： Slatko BE,Hiraizumi Y

更新日期：1975-10-01 00:00:00

abstract：:Mutants arising spontaneously from sporulated cultures of certain strains of yeast, Saccharomyces cerevisiae, contained deletions of the CYC1 gene which controls the primary structure of iso-1-cytochrome c. At least 60 different kinds of deletions were uncovered among the 104 deletions examined and these ranged in len...

journal_title：Genetics

authors： Sherman F,Jackson M,Liebman SW,Schweingruber AM,Stewart JW

更新日期：1975-09-01 00:00:00

abstract：:A sulfonamide-resistant mutant of pneumococcus, sulr-c, displays a genetic instability, regularly segregating to wild type. DNA extracts of derivatives of the strain possess transforming activities for both the mutant and wild-type alleles, establishing that the strain is a partial diploid. The linkage of sulr-c to st...

journal_title：Genetics

authors： Ledbetter ML,Hotchkiss RD

更新日期：1975-08-01 00:00:00

abstract：:In order to define more precisely the most proximal portion of chromosome 3R in Drosophila melanogaster, several new chromosome aberrations involving this region have been recovered and analyzed. These new arrangements were recovered as induced reversions of two dominant mutations, ANTPNs and dsxD, located in the regi...

journal_title：Genetics

authors： Duncan IW,Kaufman TC

更新日期：1975-08-01 00:00:00

abstract：:At pH 6.8, a substantial fraction of recombinant colonies obtained from conjugation with an HfrH donor contained multiple recombinant classes in a single colony (polygenotype colony). In contrast, when the conjugation was performed at pH 7.6, the number of polygenotypic colonies was drastically reduced, and the recomb...

journal_title：Genetics

authors： Ou JT

更新日期：1975-07-01 00:00:00

abstract：:DNA repair of single-strand breaks (produced by ionizing radiation) and of base damage (produced by ultraviolet (UV) light) are two repair mechanisms that most mammalian cells possess. Genetic defects in these repair mechanisms are exemplified by cells from the human premature-aging disease, progeria, which fail to re...

journal_title：Genetics

authors： Cleaver JE,Bootsma D,Friedberg E

更新日期：1975-06-01 00:00:00

abstract：:In a recent not in this journal (MARUYAMA 1973), one of us has considered, for a certain genetic model, the variance of the distribution of the number of loci having a given gene frequency. The formula given is incorrect. This brief note considers this problem and notes the correct solution in one particular case. ...

journal_title：Genetics

authors： Ewens WJ

更新日期：1975-05-01 00:00:00

abstract：:Recessive lethan mutations in the 3A1 to 3C2 region of the X-chromosome of Drosophila melanogaster were detected in 113 of 33,544 sperm treated by feeding 5 mM methyl methanesulfonate in 1% sucrose for 22 hours. Seven of the 113 lethans were sterile, leaving 106 for analysis by complementation tests. With only one exc...

journal_title：Genetics

authors： Liu CP,Lim JK

更新日期：1975-04-01 00:00:00

abstract：:A sample of 16 Minutes, representing 12 loci distributed over all the chromosome arms and including 3 pairs of alleles and 4 deficiencies, has been studied with respect to several developmental and recombinational parameters. Cell marker mutants located in most of the chromosome arms were used to assess (1) spontaneou...

journal_title：Genetics

authors： Ferrus A

更新日期：1975-04-01 00:00:00

abstract：:This paper studies the properties of a new class of demographic parameters for age-structured populations and analyzes the effect of natural selection on these parameters. Two new demographic variables are introduced: the entropy of a population and the reproductive potential. The entropy of a population measures the ...

journal_title：Genetics

authors： Demetrius L

更新日期：1975-03-01 00:00:00

abstract：:Genic heterozygosity and variation were studied in the permanent translocation heterozygotes Oenothera biennis I, Oe. biennis II, Oe. biennis III, Oe. strigosa, Oe. parviflora I, Oe. parviflora II, and in the related bivalent formers Oe. argillicola and Oe. hookeri. From variation at 20 enzyme loci, we find that trans...

journal_title：Genetics

authors： Levy M,Levin DA

更新日期：1975-03-01 00:00:00

abstract：:About 450 black rats (Rattus rattus) were collected from 25 localities in Asia and Oceania. Their serum transferrins were analyzed by a newly developed thin layer acrylamide gel electrophoresis accompanied with acrinol pretreatment, exhibiting 12 transferrin bands. Generally, Asian type rats (2N=42) had fast-moving tr...

journal_title：Genetics

authors： Moriwaki K,Kato H,ImalH,Tsuchiya K,Yosida T

更新日期：1975-02-01 00:00:00

abstract：:We have isolated a new class of deletion mutants of phage lambda that extend from the prophage attachment site, att, into the gam and cIII genes. In this respect they are similar to certain of the lambda pbio transducing phage, but they differ in having a low burst size and in forming minute plaques. Lytically grown s...

journal_title：Genetics

authors： Henderson D,Weil J

更新日期：1975-02-01 00:00:00

abstract：:Three sex-transforming genes (ix, tra-D, and dsx) in D. melanogaster were examined with respect to possible interactions with the NSR strain SR-spirochetes. The SR-spirochetes exerted a lethal effect on XY but not on XX individuals, regardless of whether they were phenotypically males, intersexes, or females. These re...

journal_title：Genetics

authors： Miyamoto C,Oishi K

更新日期：1975-01-01 00:00:00

abstract：:A location of the structural gene(s) for dopa decarboxylase (EC 4.1.1.26) is proposed on the basis of enzyme determinations in a set of duplication-bearing aneuploids, which revealed only one dosage-sensitive region in the Drosophila genome. This region lies between 36EF and 37D on the left arm of chromosome 2. ...

journal_title：Genetics

authors： Hodgetts RB

更新日期：1975-01-01 00:00:00

abstract：:Amoebae of the Colonia (CL) strain, which normally produce plasmodia in clones, are shown to cross with mt3 and mt4 amoebae under appropriate conditions. Strains carrying mt3 and mt4 in a CL genetic background were constructed and used in the genetic analysis of mutants isolated in CL. ...

journal_title：Genetics

authors： Adler PN,Holt CE

更新日期：1974-12-01 00:00:00

abstract：:Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variati...

journal_title：Genetics

authors： Berger EM,Weber L

更新日期：1974-12-01 00:00:00

abstract：:We have isolated 15 spontaneous mutants resistant to one or several antibiotics like chloramphenicol, erythromycin and spiramycin. We have shown by several criteria that all of them result from mutations localized in the mitochondrial DNA. The mutations have been mapped by allelism tests and by two- and three-factor c...

journal_title：Genetics

authors： Netter P,Petrochilo E,Slonimski PP,Bolotin-Fukuhara M,Coen D,Deutsch J,Dujon B

更新日期：1974-12-01 00:00:00

abstract：:Conditional lethal mutant systems developed in T-even bacteriophages T2, T4 and T6 have been used to study the partial exclusion which characterizes mixed infections of these phages. In bacteria mixedly infected with T2 and T4, the dominant phage (T4) acts against localized exclusion sensitivity determinants in the ge...

journal_title：Genetics

authors： Russell RL,Huskey RJ

更新日期：1974-12-01 00:00:00

abstract：:Two large, stable populations (Texas and Japan) of Drosophila melanogaster were surveyed at 21 allozyme loci on the second and third chromosomes and for chromosomal gene arrangements on those two chromosomes. Over 220 independent gametes were sampled from each population. The types and frequencies of the surveyed gene...

journal_title：Genetics

authors： Langley CH,Tobari YN,Kojima KI

更新日期：1974-11-01 00:00:00

abstract：:Over 100 regulatory mutations linked to the histidine (his) operon of S. typhimurium have been isolated. They all map in a region estimated to be several hundred base pairs in length located at one end of the his operon ("the hisO region"). The mutations are located at sixteen recombinationally separable sites or are ...

journal_title：Genetics

authors： Ely B,Fankhauser DB,Hartman PE

更新日期：1974-10-01 00:00:00

abstract：:Mutants of Neurospora crassa have been isolated that lack the repressible alkaline phosphatase, but, unlike nuc-1 and nuc-2 mutants, are able to make the repressible acid phosphatase and the repressible phosphate permease under conditions of derepression (phosphate deprivation). The new mutants, called pho-2, map in L...

journal_title：Genetics

authors： Gleason MK,Metzenberg RL

更新日期：1974-10-01 00:00:00

abstract：:The conflicts between science and morals which still continue to arise despite the apparent hegemony of atheistic scientism over traditional Judeo-Christianity in the twentieth century reflect a basic contradiction in the metaphysical foundation of Western lives. As was set forth by Machiavelli, the contradiction inhe...

journal_title：Genetics

authors： Stent GS

更新日期：1974-09-01 00:00:00

abstract：:The T4 mutations px, y and 1206 inactivate an error-prone recombination-like repair system, reducing or abolishing mutagenesis by UV irradiation, MMS, and white light irradiation in the presence of the photosensitizer 8MOP. Both px and y increase some spontaneous mutation rates and slightly enhance proflavin mutagenes...

journal_title：Genetics

authors： Green RR,Drake JW

更新日期：1974-09-01 00:00:00

abstract：:Availability of animal protein for human consumption is very low in the developing countries mainly because of low productivity of existing livestock; ways and means to improve productivity through breeding are discussed and some basic issues requiring further research pointed out. ...

journal_title：Genetics

authors： Rendel J

更新日期：1974-09-01 00:00:00

abstract：:Translocation induced in the immature oocyte, in meiotic prophase, affects division I orientation and segregation, the usual result being that the two halves of translocations are directed to opposite poles. Since interchange is usually (if not exclusively) between chromatids, this is to be expected from the creation ...

journal_title：Genetics

authors： Parker DR,Williamson JH

更新日期：1974-09-01 00:00:00

abstract：:Seven hundred and three second chromosomes were extracted from a Raleigh, North Carolina population of Drosophila melanogaster in 1970. Additionally, four hundred and eighty-nine third chromosomes were extracted from a large cage population founded from the flies in the 1970 Raleigh collection. The alpha glycerol-3-ph...

journal_title：Genetics

authors： Muki T,Watanabe TK,Yamaguchi O

更新日期：1974-08-01 00:00:00

abstract：:A technique has been perfected for enabling good microscope preparations to be obtained from the larval ganglia of Drosophila melanogaster. This system was then tested with X-rays and an extensive series of data was obtained on the chromosome aberrations induced in the various stages of the cell cycle.-The analysis of...

journal_title：Genetics

authors： Gatti M,Tanzarella C,Olivieri G

更新日期：1974-08-01 00:00:00

abstract：:Repair replication of DNA has been studied in first instar larvae of Drosophila melanogaster with isopycnic centrifugation techniques. Larvae were fed BUdR, FUdR, streptomycin, penicillin, and Fungazone for two to four hours prior to exposure to UV, X-rays, MMS, or EMS. Feeding was continued for four hours in the pres...

journal_title：Genetics

authors： Boyd JB,Presley JM

更新日期：1974-08-01 00:00:00